How a Little Blue Pill Changed the World Viagra (sildenafil) is one of the most widely-known prescription drug names on the U.S. market.To get more news about vigrx plus where to buy, you can visit vigrxplus-original.com official website. Often dubbed "the little blue pill", Viagra (sildenafil) was the first phosphodiesterase 5 (PDE5) inhibitor approved to treat erectile dysfunction (ED). ED is a common sexual problem for men and its frequency increases with age. Pfizer promoted Viagra and ED awareness via direct-to-consumer (DTC) advertising, which prompted men to seek medical advice and a prescription from their doctors. For many men, the stigma and embarrassment of talking to their doctor about ED has declined since the introduction of Viagra and other PDE5 inhibitors. In a survey published in BMJ, 62 percent of men reported a decline in self esteem, 29 percent reported a negative effect on a relationship, and 21 percent reported that their relationship had ceased due to ED. When a man is aroused, muscles in the penis relax to allow greater blood flow. Viagra helps to elevate the levels of a substance known as cyclic guanosine monophosphate (or cGMP) that causes the tissues to relax, leads to an inflow of blood, and causes an erection with sexual stimulation. Viagra and other PDE5 inhibitors like Cialis, Levitra (brand discontinued), Stendra and Staxyn treat erectile dysfunction (ED), but do not directly increase a man's sexual desire. The dose may be adjusted based on doctor recommendations, but it should not exceed 100 mg per dose and should not be taken more than once per day. Staying with the lowest dose possible may help to lessen side effects. A physician will prescribe your specific dose. |
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